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Thursday, May 19, 2022
| 14:00 – 14:05 | Welcome Address: Michael Synowitz (Co-Chair), UKSH, Kiel) |
| 14:05 – 15:25 | Session I Chair: Susanne Wolf (Charité, Berlin) |
| 14:05 – 14:45 | Plenary Lecture I Gabriele Bergers (VIB-KU Leuven Center for Cancer Biology, Belgium) METABOLIC TRAITS OF GLIOMA INVASION |
| Oral Presentations I | |
| 14:45 – 15:05 | Katarzyna Leszczynska (Neurobiology Center, Nencki Institute of Experimental Biology, Warsaw, Poland)
Hypoxia drives repression of multiple pathways through epigenetic reprogramming of glioblastoma |
| 15:05 – 15:25 | Agnieszka Chryplewicz (Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of TechnologyLausanne, Switzerland) CO-TARGETING AUTOPHAGY, MACROHAGES AND VASCULATURE IN GLIOMA TUMORS TRIGGERS IMMUNOGENICITY |
| 15:25 – 16:10 | Poster Session and Coffee Break |
| 16:10 – 17:40 | Session II Chair: Michela Serresi (MDC, Berlin) |
| 16:10 – 16:50 | Plenary Lecture II Manuel Valiente (CNIO - Centro Nacional de InvestigacionesOncológicas, Madrid, Spain) EXPLOITING THE TRANSLATIONAL POTENTIAL OF ESTABLISHED AND NEW BRAIN METASTASIS MODELS |
| Oral Presentations II | |
| 16:55 – 17:10 | Lisa Sevenich (Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany) DISSECTING THE ROLE OF CSF2Rb-STAT5 SIGNALING IN TUMOR-ASSOCIATED INFLAMMATION IN BRAIN METASTASIS |
| 17:10 – 17:30 | Philip Schmassmann (Department of Biomedicine, University of Basel, Switzerland) MICROGLIA-SPECIFIC DISRUPTION OF SIALIC ACID-SIGLEC-9/E INTERACTIONS: A NOVEL IMMUNOTHERAPY AGAINST GLIOBLASTOMA? |
| 17:30 – 18:15 | Poster Session and Coffee Break |
| 18:15 – 19:35 | Session III Chair: Charlotte Flüh (UKSH, Kiel) |
| 18:15 – 18:55 |
Plenary Lecture III Itay Tirosch (Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel) DISSECTING INTRA-TUMOR AND INTER-TUMOR HETEROGENEITY IN GLIOMA |
| Oral Presentations III | |
| 18:55 – 19:15 | Jasim Kada Benotmane (Neurosurgery, Albert-Ludwigs-University Freiburg, Germany) SPATIALLY RESOLVED T-CELL RECEPTOR SEQUENCING (SPTCR-SEQ) UNCOVERS REGIONAL DIVERSITY OF ANTI-TUMOR IMMUNE RESPONSES |
| 19:15 – 19:35 | Björn Brändl (Zentrum für Integrative Psychiatrie -ZIP Kiel, Kiel, Germany) IntraEpiGliom- Rapid sequencing-based diagnosis of brain tumors |
| 20:00 | Reception at the Stadtgut Buch Barn |
Friday, May 20, 2022
| 9:00 – 9:40 | Session IV Chair: Gaetano Gargiulo (MDC, Berlin) |
| 9:00 – 9:40 |
Plenary Lecture IV Giulio F. Draetta (Genomic Medicine Department, Unit 1954, The University of Texas MD Anderson Cancer Center, Houston, USA) A NOVEL POTENTIAL THERAPEUTIC TARGET IN GLIOBLASTOMA |
| 9:40 – 10:20 | Poster Session and Coffee Break |
| 10:20 – 11:40 | Session V Chair: Pilar Sanchez (MDC) |
| 10:20 – 11:00 | Plenary Lecture V Marcel Kool (Kitz Hopp Children's Cancer Center, Heidelberg, Germany) PEDIATRIC BRAIN TUMORS: HOW TO TRANSLATE ALL THE MOLECULAR DATA INTO SUCCESSFUL TREATMENTS FOR PATIENTS? |
| Oral Presentations IV | |
| 11:00 – 11:20 | Ilon Liu (Pediatric Oncology, Dana-Farber Cancer Institute, Boston, USA) THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION |
| 11:20 – 11:40 |
Catia Neto (School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK) AN IPSC-DERIVED MULTICELLULAR PLATFORM TO STUDY BRAIN TUMOURS |
| 11:40 – 12:30 | Lunch (Cafeteria) and Poster Session |
| 12:30 – 13.50 | Session VI Chair: Christoph Harms (Charité, Berlin) |
| 12:30 – 13:10 |
Plenary Lecture VI Rainer Glass (NeurochirurgischeForschung am Klinikum der Universität München, Germany) CONVERTING NFKB INTO A TUMOR-SUPPRESSOR |
| Oral Presentations V | |
| 13:10 – 13:30 | Raphaela Pensch (Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden) LEVERAGING EVOLUTIONARY CONSTRAINT TO IDENTIFY PUTATIVE NON-CODING DRIVERS IN GLIOBLASTOMA |
| 13:30 – 13:50 | Davide Ceresa (Cellular Oncology Unit, IRCCS S.Martino - IST Genova, Genova, Italy) MYC-DRIVEN GAME OF CLONES IN GLIOBLASTOMA PROGRESSION REVEALED BY GENETIC BARCODING |
| 13:50 – 14:30 | Poster Session and Coffee Break |
| 14:30 – 16:10 | Session VII Chair: Matthias J. Schmitt (MDC, Berlin) |
| Oral Presentations VI | |
| 14:30 – 14:50 | Kieron White (Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland) TRANSCRIPTOMIC ANALYSIS REVEALS NOVEL TUMOUR MICROENVIRONMENT SUBTYPES IN ISOCITRATE DEHYDROGENASE WILDTYPE GLIOBLASTOMA |
| 14:50 – 15:10 | Aviel Iluz (Department of Neurology, Hadassah Medical Center, Hebrew University of Jerusalem, Israel) THE USE OF METHYLATION FINGERPRINTS TO INVESTIGATE THE CELL-OF-ORIGIN OF GLIOMAS |
| 15:10 – 15:30 | Valentina Pieri (IRCCS San Raffaele Scientific Institute, Milan, Italy) PLASMA CFDNA LIQUID BIOPSY IN THE FOLLOW-UP OF HIGH-GRADE GLIOMAS |
| 15:30 – 16:10 | Plenary Lecture VII Antonio Iavarone (Institute for Cancer Genetics, Columbia University Medical Center, New York, USA) MECHANISMS OF ONCOGENESIS AND PRECISION MEDICINE OF GLIOBLASTOMA |
| 16:10 – 16:15 | Awarding of Poster Prizes |
| 16:15 | Departure |
Our partners
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Partner Organisations:
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European Association of NeuroOncology |
British Neuro-Oncology Society
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